The Pediatric Initiative Network (PIN), a subgroup of the Oncofertility Consortium (OFC), is an international group of providers dedicated to preserving and protecting the fertility of children and adolescents at risk for infertility due to medical conditions or treatments. The PIN meets during the annual Oncofertility Consortium meeting and/or via quarterly group conference calls. Please email for more information, or to join the PIN.

Activities of the PIN typically occur within 3 committees: Best Practice Committee, Research Committee and Education Committee.

Best Practice Committee - The mission of the Best Practice Committee is to develop strategies to optimize fertility related care for at-risk youth. The committee generally adopts 1-2 new projects annually based on participants’ interest. The work of the committee includes literature review, survey design and administration and working group conference calls. Previous projects have included the development of a stratification system for risk for future infertility after gonadotoxic treatment (Meacham 2020 JAYAO) and literature review and a survey of the OFC to ascertain current practice in use of AMH to guide clinical practice. The Navigation Committee is a subcommittee of the Best Practice Committee and addresses issues related to optimizing access to fertility preservation through the use of Navigators.

Research Committee - The mission of the Research committee is to design and implement collaborative multi-site research studies to advance fertility related care for at-risk youth. Recent/ongoing projects –

Ovarian Tissue Cryopreservation (OTC) Database- Limited dataset and information regarding patients who have undergone OTC is being entered into a secure RedCap database housed at NortonHealth in Lousiville, KY. Members of the PIN who wish to collaborate are to submit a local IRB for collection of this information, then will have access to this multicenter database for queries. Research proposals are to be submitted to the PIN Research Committee and projects will be decided as a group among members who are part of the study group.

Those interested in enrolling their patients in this database may contact: Dr. Maggie Dwiggins at or Stacey Nalley at

NICHD/Oncofertility Ovarian Tissue Image Library- an image library of H&E stained slides has been created with slides from the original NPC tissues. Additional members of the PIN who are collecting ovarian tissue for research will be adding slides to this image bank.

Investigators who want add to this image library or to use the NICHD/Oncofertility Ovarian Tissue Image Databank for research may contact Dr. Veronica Gomez-Lobo at

For researchers interested in access to ovarian tissue- The PIN Research Committee has compiled a list of sites collecting gonadal tissue for research and funded gonadal tissue investigators.

If you are interested in being listed or need access to tissue or collaborators, you may contact Dr. Mary Zelinski at

Education Committee - The mission of this committee is to improve patient and clinician communication and resources about fertility and reproductive health. We aim to achieve these goals through an international consortium of clinicians, educators, and researchers who will share and develop educational materials, resources, and strategies for improving clinician communication and patient knowledge on fertility and reproductive health considerations in at-risk populations. 

Current PIN Leadership:

PIN CHAIR: Leena Nahata, M.D. is an Associate Professor of Clinical Pediatrics at The Ohio State University, board-certified pediatric endocrinologist at Nationwide Children’s Hospital, and the founder and Medical Director of the Fertility and Reproductive Health Program at Nationwide Children’s Hospital. As an NIH-funded Principal Investigator in the Center for Biobehavioral Health at the Abigail Wexner Research Institute at Nationwide Children’s Hospital, she is conducting several clinical research studies to examine outcomes and predictors of fertility preservation utilization in pediatric populations at risk for infertility, including youth with cancer, differences of sex development, and gender dysphoria. She is a member of the Children’s Oncology Group and PanCareLIFE male fertility preservation task forces, and the Reproductive Health chapter lead for the World Professional Association for Transgender Health Standards of Care Version 8.

PIN VICE-CHAIR: Molly Moravek, M.D., M.P.H. is an Associate Professor in the departments of Obstetrics and Gynecology and Urology at the University of Michigan.  She is a board-certified Reproductive Endocrinologist and is the Director of the Fertility Preservation Program at Michigan Medicine, where she also serves as the IVF Medical Director. Her research interests include long-term outcomes of fertility preservation, transgender care and fertility, ovarian tissue cryopreservation and reimplantation techniques, access to fertility care, and fertility and hormone replacement in cancer survivors. She is active in both translational and clinical research and has received funding from the American Society for Reproductive Medicine and the NIH to study fertility and fertility preservation in a transgender mouse model. She also chairs the LGBTQ Special Interest Group of the American Society for Reproductive Medicine.

Best Practice Committee Chair: Lillian Meacham, M.D. is a Professor of Pediatrics and a pediatric endocrinologist who is the program director for the Fertility Preservation and Reproductive Health Program for the Aflac Cancer and Blood Disorders Center at Children’s Healthcare of Atlanta.  She has worked on national (COG Long-Term Follow-Up Guideline) and international committees (International Harmonization Group) in the area of gonadal late effects. She has over 30 years of experience treating endocrine late effects of cancer therapy.

Best Practice Committee Vice-Chair: Holly Hoefgen, M.D. is Assistant Professor of Obstetrics and Gynecology within the Division of Pediatric and Adolescent Gynecology at Washington University School of Medicine in St. Louis. She is also the co-founder and co-director of the Integrated Care & Fertility Preservation Program at St. Louis Children’s Hospital. Her academic interests include ovarian tissue preservation, improving access to fertility preservation and gynecologic late effects of gonadotoxic treatments in this population.

Navigator Subcommittee Chair: Stacy Whiteside, CPNP-AC, leads the subcommittee of fertility preservation navigators dedicated to improving access to fertility related care for at-risk youth. Stacy is an Oncology Advanced Practice Nurse and serves as the full-time fertility preservation navigator at Nationwide Children’s Hospital in Columbus, OH.

Research Committee Chair: Veronica Gomez-Lobo, M.D. is the Director of Pediatric and Adolescent Gynecology at the Eunice Kennedy Shriver National Institute of Child Health and Human Development. She is the site PI for the Disorder of Sex Development-Translational Research Network and has recently developed a multi-site ovarian tissue cryopreservation database. She served as President of the North American Society for Pediatric and Adolescent Gynecology (NASPAG) in 2016-2017.

Research Committee Vice-Chair: Krista Childress, M.D. is an Assistant Professor of Gynecology and Obstetrics within the Division of Gynecologic Specialties at Emory University, and has secondary appointments in Pediatric Surgery and Pediatrics at Children’s Healthcare of Atlanta (CHOA). She is a member of the fertility preservation program at CHOA and an active member of the North American Society for Pediatric and Adolescent Gynecology (NASPAG).

Research Committee Vice-Chair: Maggie Dwiggins, M.D. is Director of Oncofertility at Norton Healthcare associated with the University of Louisville division of pediatrics and a Pediatric and Adolescent Gynecologist at Norton Children’s Medical Group. She is an active member of the North American Society for Pediatric and Adolescent Gynecology (NASPAG).

Education Committee Chair: Gwendolyn P. Quinn, Ph.D. is the Livia Wan Endowed Chair and Professor in the departments of OB-GYN, Population Health and the Division of Medical Ethics at the Grossman School of Medicine, New York University. She is a health outcomes researcher with a focus on patient clinician communication in reproductive health and oncology.

Education Committee Vice-Chair: Antoinette Anazodo, M.D., Ph.D. is a pediatric and adolescent oncologist and the Director of AYA Cancer at Sydney Children’s and Prince of Wales Hospital. She is the chair for the Australian AYA fertility preservation group and guidelines group and leads the Future Fertility research program on reproductive concerns of cancer patients.

Past PIN Chair: Leslie Coker Appiah, M.D. is an Associate Professor of Obstetrics and Gynecology at the University of Colorado Denver | Anschutz Medical Campus and a member of the Section of Pediatric and Adolescent Gynecology at Children’ Hospital Colorado (CHCO). She is the Director of the Fertility Preservation and Reproductive Late Effects Program at the Colorado Cancer Center and the Center for Cancer and Blood Disorders at CHCO. Dr. Appiah is an American Society for Reproductive Medicine (ASRM) Clinical Reproductive Scientist Training (CREST) Scholar and chairs several national committees dedicated to reproductive health. Her research interests include fertility preservation and risk reduction in the CAYA population, hormone replacement therapy in chemotherapy induced ovarian insufficiency and gynecologic care in survivorship.

Recent PIN Committee publications:

1. Moravek MB, Appiah LC, Anazodo A, Burns KC, Gomez-Lobo V, Hoefgen HR, Jaworek Frias O, Laronda MM, Levine J, Meacham LR, Pavone ME, Quinn GP, Rowell EE, Strine AC, Woodruff TK, Nahata L. Development of a Pediatric Fertility Preservation Program: A Report From the Pediatric Initiative Network of the Oncofertility Consortium. J Adolesc Health. 2019 May;64(5):563-573. doi: 10.1016/j.jadohealth.2018.10.297. Epub 2019 Jan 14. PMID: 30655118; PMCID: PMC6478520.

2. Nahata L, Woodruff TK, Quinn GP, Meacham LR, Chen D, Appiah LC, Finlayson C, Orwig KE, Laronda MM, Rowell EE, Anazodo A, Frias O, Rios JS, Whiteside S, Gomez-Lobo V, Dwiggins M, Childress KJ, Hoefgen HR, Levine JM, Jayasinghe Y, Moravek M. Ovarian tissue cryopreservation as standard of care: what does this mean for pediatric populations? J Assist Reprod Genet. 2020 Jun;37(6):1323-1326. doi: 10.1007/s10815-020-01794-7. PMID: 32390071; PMCID: PMC7311630.

3. Nahata L, Gomez-Lobo V, Meacham L, Appiah L, Childress K, Hoefgen H, Dwiggins M, Whiteside S, Bjornard K, Rios J, Anazodo A, Finlayson C, Frias O, Woodruff T, Moravek M. 2019 Pediatric Initiative Network: Progress, Proceedings, and Plans. J Adolesc Young Adult Oncol. 2020 Aug;9(4):457-463. doi: 10.1089/jayao.2020.0020. Epub 2020 May 27. PMID: 32460662; PMCID: PMC7415883.

4. Meacham LR, Burns K, Orwig KE, Levine J. Standardizing Risk Assessment for Treatment-Related Gonadal Insufficiency and Infertility in Childhood Adolescent and Young Adult Cancer: The Pediatric Initiative Network Risk Stratification System. J Adolesc Young Adult Oncol. 2020 Dec;9(6):662-666. doi: 10.1089/jayao.2020.0012. Epub 2020 May 26. PMID: 32456570.

5. Nahata L, Anazodo A, Cherven B, Logan S, Meacham LR, Meade CD, Zarnegar-Lumley S, Quinn GP. Optimizing Health Literacy to Facilitate Reproductive Health Decision-making in Adolescent and Young Adults with Cancer. Pediatr Blood Cancer. 2020 Jul 6:e28476. doi: 10.1002/pbc.28476. Epub ahead of print. PMID: 32633029.

6. Frederick NN, Lehmann V, Ahler A, Carpenter K, Cherven B, Klosky JL, Nahata L, Quinn GP. Psychosexual Functioning in Cancer Survivorship. 2020: e28437. doi: 10.1002/pbc.28437. Epub ahead of print.

7. Burns K, Appiah L, Schmidt S, Franklin A, Saraf A, Anazodo A. Male Pediatric and AYA Reproductive Survivorship. Pediatr Blood Cancer. In Press.

8. Whiteside S, Frias O, Clifford L, Schultz K, Erickson L, Caldwell M, Prebus O, Smith K. Oncofertility Patient Navigation: The Frontlines of Fertility and Reproductive Health Care in Cancer. Pediatr Blood Cancer. In Press.