A publication in Human Reproduction highlights the ability to culture secondary follicles from cryopreserved macaque ovarian tissue. The authors Ting, Yeoman, Lawson, and Zelinski compared ovarian tissue after slow-freezing or vitrification and found that vitrification appeared to better maintain the morphology of stromal cells and secondary follicles, and the ability to form an antrum during 3D follicle culture. The paper, “In vitro development of secondary follicles from cryopreserved rhesus macaque ovarian tissue after slow-rate freeze or vitrification,” demonstrates, for the first time, the ability to maintain, grown, form an antrum, and produce steroid hormones, from macaque follicles derived from cryopreserved ovarian tissue.
