Latest News
New Oncofertility Publication: Embryonic Fibroblasts Enable the Culture of Primary Ovarian Follicles Within Alginate Hydrogels
May 4, 2012
In a recent publication in Tissue Engineering, Oncofertility Consortium researchers examined the use of mouse embryonic fibroblasts (MEFs) in conjunction with a 3D-hydrogel-supported culture of ovarian follicles. Authors, Tagler, Tu, Smith, Anderson, Tingen, Woodruff, and Shea, found that coculture with the MEFs resulted in the…
New Publication Online: Fibrin encapsulation and vascular endothelial growth factor delivery promotes ovarian graft survival in mice
May 4, 2012
In a publication in Tissue Engineering, Oncofertility Consortium researchers identified new methods that may be utilized to increase the success of ovarian transplantation after cryopreservation. When ovarian tissue is transplanted back into a woman who preserved her fertility, revascularization of the tissue takes some time,…
New Publication Online: Animal age, weight and estrus cycle stage impact the quality of in vitro grown follicles
May 4, 2012
In a publication from Human Reproduction, Oncofertility Consortium researchers investigate how common patient-specific variables, such as age, weight, and stage in the menstrual cycle, may affect the culture of ovarian follicles. Authors, Hirshfeld-Cytron, Duncan, Xu, Jozefik, Shea, and Woodruff examined how in vitro follicle growth…
Response Piece in Journal of Adolescent and Young Adult Oncology from Oncofertility Researcher, Gwendolyn Quinn
May 3, 2012
The field of adolescent and young adult oncology (AYAO) is developing and evolving, providing fertile ground for debate, discussion and the exchange of opinions. In the “Controversies” feature of the Journal of Adolescent and Young Adult Oncology, the editors pose a key AYAO question to…
Oncofertility Consortium Members, Jessica Hornick, Francesca Duncan, Lonnie Shea and Teresa K. Woodruff, Publish New Study in the Journal of Human Reproduction
May 1, 2012
In this new study, the authors used the characteristic architecture of the rhesus macaque ovary, which is similar to the human ovary in terms of morphology and physiology, to devise robust isolation and culture methods for primate primordial follicles. Primordial follicles are con- fined to…
New Publication by Oncofertility Consortium Researchers, Gwendolyn P. Quinn, Caprice Knapp, Devin Murphy, Kelly Sawczyn and Leonard Sender
May 1, 2012
Survival takes precedence for adolescent patients with cancer and their families. Patients may not discuss their treatments’ potential to damage their reproductive capacity, which has significant psychological late effects in survivorship. This new study aims to identify whether a health-related quality of life (HRQoL) instrument intended…