Prevalence The prevalence of X-linked adrenoleukodystrophy (X-ALD) is 1 in 20,000 to 50,000 individuals worldwide. This condition occurs with a similar frequency in all populations[1]. Natural History X-ALD is an X-linked recessive inherited condition that primarly affects males (females are carriers). It is due to…
Prevalence The prevalence of alpha-mannosidosis is not precisely known. It is estimated that alpha-mannosidosis occurs in approximately 1 in 500,000[1] to 1 in 1,000,000 live births and is expected to be found in every ethnic group[2]. Natural History Alpha-mannosidosis is a rare-lysosomal storage disorder than…
Our center was established in 1987 and since then it offered all the fertility services available at any given time. The first fertility preservation service for women (embryo freezing) was offered to our patients in 1991 and was supplemented with the addition of the (…
The group was founded in 2000. Main focuses Cryopreservation (freezing and thawing) of whole ovary with blood vessels Cancer is one of the major death causes in the world. The overall incidence rate for cancer in children aged 14 years and younger increased by 0.6%…
Voluntary Oncofertility group in Lithuania was founded in the middle of 2014. Group founded by children hematologists dr. Goda Vaitkeviciene and dr. Jelena Rascon, scientist in oncology dr. Zivile Gudleviciene, urologists Ausvydas Patasius and Gilvydas Verkauskas and gynecologist dr. Zana Bumbuliene. In 2014 Program for…
Today, improved treatments of cancer and other diseases give patients the hope of long term survival. However, many of the treatments that increase survival may cause loss of fertility. New technologies in reproductive medicine are providing possibilities for preserving fertility. Lurie Children’s is dedicated to…
Pediatric and Adolescent Committee (PAC) – formally known as the Pediatric Initiative Network (PIN) is one of the scientific committees of the Oncofertility Consortium (OFC). It’s an international group of providers dedicated to preserving and protecting the fertility of children and adolescents at risk for…
Director of the Oncofertility Consortium and Assistant Professor, Department of Obstetrics, Gynecology and Reproductive Biology, Michigan State University Prior to joining MSU as the Director of the Oncofertility Consortium in January 2021, Dr. Mahmoud Salama was an Adjunct Assistant Professor of Obstetrics & Gynecology (OBGYN),…
Application of an alginate 3-D culture system to the maturation of primate follicles in vitro and delivery of pro-angiogenic agents to autotransplanted ovarian tissue
The application of biomaterials and tissue engineering to reproductive biology provides an enabling technology that is central to the Oncofertility Consortium
Prior to joining MSU OBGYN as Assistant Professor and Director of the Oncofertility Consortium in January 2021, Dr. Mahmoud Salama was an Adjunct Assistant Professor of Obstetrics & Gynecology (OBGYN), at Northwestern University, USA (2018-2020). Dr. Salama got his MBBCh of Human Medicine and Surgery…
Abstract An option for fertility preservation for women facing a cancer diagnosis involves the cryopreservation of ovarian tissue for later re-transplantation or in vitro culture, with in vitro culture preferred to avoid reintroduction of the cancer. Small, immature follicles survive the freeze-thaw process, and can…
Abstract Children and women of reproductive age are increasingly surviving cancer diagnoses, and therefore long-term quality-of-life issues are of greater importance at the time of diagnosis. Cancer therapies including radiation and chemotherapy can be detrimental to fertility, and therefore many patients are motivated to preserve…
Co-editors Clarisa Gracia and Teresa K. Woodruff Forward by Roger A. Lobo, MD Part I: Fertility Risks for Cancer Patients Gonadotoxicity of Cancer Therapies in Pediatric and Reproductive-Age Females by Jennifer Levine Gonadotoxicity of Cancer Therapies in Pediatric and Reproductive-Age Males by Jill P. Ginsberg…
Female cancer patients who seek fertility preservation but cannot undergo ovarian stimulation and embryo preservation may consider: 1) retrieval of immature oocytes followed by in vitro maturation (IVM); 2) ovarian tissue cryopreservation followed by transplantation or in vitro follicle culture (IVFC). Conventional IVM is carried…
Abstract BACKGROUND: Ovarian tissue cryopreservation is an emerging fertility preservation option, and culturing follicles isolated from this tissue to obtain mature gametes may ultimately be the best solution for patients for whom transplantation is contraindicated. It is unclear, however, how patient-specific variables (including age, weight…
Stine Kristensen, PhD, Rigshospitalet Ovarian Tissue Cryopreservation (OTC) and aging Marie-Madeleine Dolmans, MD, PhD, Université Catholique de Louvain Ovarian Tissue Cryopreservation (OTC) and live births Rod T. Mitchell, PhD, University of Edinburgh Fertility preservation in prepubertal boys with cancer – testicular transplantation as a future…
Dr. Mahmoud Salama, Assistant Professor, Professorship-Fellow at Department of Gynecology and Obstetrics, Medical Faculty, University of Cologne, Germany, who is also an Oncofertility Global Partners Network representative from Egypt and Germany, recently published an article in Clinical Reviews of Oncology/Hematology. The article ‘Updates in preserving…
Leader of the Brazilian Oncofertility Consortium Wins a Recognized Research Prize in Brazil Dr. Jhenifer Rodrigues recently was awarded a prestigious prize for her PhD disseration. Below is a blog from Dr. Rodrigues highlighting her success: By Jhenifer Rodrigues, PhD The researcher and leader of…
In the coming days and weeks, we will highlight different sessions of the upcoming Oncofertility Conference, Critical Conversations in Oncofertility: Pediatrics and Beyond and our wonderful speakers. Today, we’re sharing speaker bios for the Afternoon Session of November 3, 2015 which focuses on clinical research updates. ********************************************************* Gracia,…
We’re now less than a month away from the 9th Annual Oncofertility Conference, Critical Conversations in Oncofertility: Pediatrics and Beyond. In the coming days and weeks, we will highlight different sessions of the meeting and our wonderful speakers. Today, we’re sharing speaker bios for the…
We’re exited to continue our new blog series to spotlight National Physicians Cooperative member institutions! If your institution is a member of the NPC, submit your information to us for development of an institution-specific page on the Oncofertility Consortium website, as well as a blog post,…